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Expedition 48 prime and backup crews are seen in quarantine behind glass, from left, Expedition 48 crewmembers Kate Rubins of NASA, Anatoly Ivanishin of Roscosmos and Takuya Onishi of the Japan Aerospace Exploration Agency (JAXA), backup crew members Peggy Whitson of NASA, Oleg Novitskiy of Roscosmos and Thomas Pesquet of the European Space Agency during the State Commission meeting to approve the Soyuz launch to the International Space Station, Wednesday, July 6, 2016 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Rubins, Ivanishin and Onishi will launch from the Baikonur Cosmodrome in Kazakhstan the morning of July 7, Kazakh time (July 6 Eastern time.) All three will spend approximately four months on the orbital complex, returning to Earth in October.