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The second International Microgravity Laboratory-2 (IML-2) is off to an ontime start as the Space Shuttle Columbia lifts off from Launch Pad 39A at 12:43:00 p.m. EDT. On board are a crew of seven and more than 80 investigations developed by more than 200 scientists from 13 countries. The IML-2 complement includes materials science, bioprocessing, space and radiation biology, and human physiology experiments that will be carried out over the course of the 14-day flight. The commander of Space Shuttle Mission STS-65 is Robert D. Cabana. James D. Halsell Jr. is the pilot; the payload commander is Richard J. Hieb; the three mission specialists are Carl E. Walz, Leroy Chiao and Donald A. Thomas. Dr. Chiaki Mukai, representing NASDA, the National Space Development Agency of Japan, is the payload specialist. Mukai becomes the first Japanese woman to fly into space.